Capsaicin is a New Gastrointestinal Mucosal Protecting Drug Candidate in Humans — Pharmaceutical Development and Production Based on Clinical Pharmacology | IntechOpen
Fight fire with fire: Neurobiology of capsaicin-induced analgesia for chronic pain - ScienceDirect
Fire in the hole: pore dilation of the capsaicin receptor TRPV1 | Nature Neuroscience
Resiniferatoxin hampers the nocifensive response of Caenorhabditis elegans to noxious heat, and pathway analysis revealed that the Wnt signaling pathway is involved | bioRxiv
Resiniferatoxin
Resiniferatoxin is 1,000 X hotter than Capsaicin (the chemical which causes the sensation of heat in chilies). : r/Damnthatsinteresting
A single TRPV1 amino acid controls species sensitivity to capsaicin | Scientific Reports
Tasting Resiniferatoxin (RTX): The Spiciest Substance in the World | Full Extraction from Euphorbia - YouTube
Functional Properties of the High-Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist (4-Hydroxy-5-iodo-3-methoxyphenylacetate ester) Iodo-Resiniferatoxin | Journal of Pharmacology and Experimental Therapeutics
New capsaicin analogs as molecular rulers to define the permissive conformation of the mouse TRPV1 ligand-binding pocket | eLife
Resiniferatoxin - Wikipedia
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin | PNAS
Resiniferatoxin: the hottest chemical you're not using | Alomone Labs
Frontiers | Regulation of Pain Genes—Capsaicin vs Resiniferatoxin: Reassessment of Transcriptomic Data
![Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol. All four... | Download Scientific Diagram](https://www.researchgate.net/publication/307954283/figure/fig10/AS:404555075473417@1473464854728/Structures-of-capsaicin-RTX-6-shogaol-and-6-gingerol-All-four-compounds-possess-a.png "Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol. All four... | Download Scientific Diagram")
Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol. All four... | Download Scientific Diagram
Selective Targeting of TRPV1 Expressing Sensory Nerve Terminals in the Spinal Cord for Long Lasting Analgesia | PLOS ONE
Resiniferatoxin - Wikipedia
![Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol. All four... | Download Scientific Diagram](https://www.researchgate.net/publication/307954283/figure/fig10/AS:404555075473417@1473464854728/Structures-of-capsaicin-RTX-6-shogaol-and-6-gingerol-All-four-compounds-possess-a_Q640.jpg "Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol. All four... | Download Scientific Diagram")
Structures of capsaicin, RTX, [6]-shogaol and [6]-gingerol. All four... | Download Scientific Diagram
Differential Activation and Desensitization of Sensory Neurons by Resiniferatoxin | Journal of Neuroscience
Understanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin | PNAS
Frontiers | Beyond Neuronal Heat Sensing: Diversity of TRPV1 Heat-Capsaicin Receptor-Channel Functions
This Chemical Is So Hot It Destroys Nerve Fibers—in a Good Way | WIRED
Molecules | Free Full-Text | Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses
